Monday, December 5, 2011

Arrow Leaf Balsam Root Through the Seasons: A monograph


Art by Lauren Raine
I know it's cliche to mention, but I swear time is swirling by faster and faster these days. I've already been snowshoeing for weeks and each time I strap on my mittens and coat I can still barely believe it. 


That's also how I felt when Kiva announced the first anniversary issue of the Plant Healer Magazine is released! Has it really been a year since this revolutionary magazine was first released? 


And I am not just being overly superlative. This magazine, in it's short year of existence, has revolutionized herbal medicine. No other publication like it has ever existed in the history of herbal medicine. 


The Plant Healer Magazine is a quarterly pdf publication that publishes a wide variety of articles from contemporary herbalists. What I love most about the magazine is the fresh perspectives from such a wide range of herbalists. It's almost like a temperature gage of what is going on NOW in the herbal world. 


From medicine making to botany to wildcrafting to midwifery to plant monographs to clinical skills to poetic ramblings about plants this magazine provides hours and hours of learning. 


The latest anniversary issue is 265 pages! Yes, that is crazy and no, they probably won't do that again. I am really excited to curl up next to the fire this winter and read article after article from many of my favorite herbalists!


To celebrate the anniversary issue, the editors of the magazine, Kiva Rose and Jesse Wolf Hardin are offering some incredible bonuses along with the regular price of subscribing. One bonus is a significant discount to attend the Traditions in Western Herbalism Conference next September! 


To learn more about subscribing and all the bonuses click on the banner below.  


Plant Healer Banner




A year ago I published my first article in the Plant Healer Magazine on a plant that is certainly the emblem for our valley: Arrow Leaf Balsam Root (Balsamorhiza sagittata). 


In celebration of the anniversary issue, here is the full article.





Balsam Root through the Seasons
I live in the Methow Valley in the northeastern cascades of Washington State. The valley is just over 50 miles long and is located a couple hours (as the crow flies) from the Canadian border and 4 hours from the Pacific Ocean. 

The valley boasts of large tracts of wilderness and a variety of ecological niches, from the sagebrush steppe to riparian rivers, to evergreen forests to alpine peaks. 

Each season in the Methow is distinct with intense variations in temperature and plant life. In May, the otherwise drab hillsides of the sagebrush steppe burst alive with a diversity of wildflowers, the most prominent being the flower of the valley, Arrowleaf Balsamroot (Balsamorhiza sagitatta). 

This wild flower of the Asteraceae family covers hillsides from April to June, peaking in the middle of May. Besides being a visual delight, this plant has played an important role in the ecology of the Methow for thousands of years. Dense roots run deep into the rocky soils, preventing erosion; large leaves provide habitat to many scurrying animals and the leaves, flowers and seeds provide an important food source to mammals as small as field mice, to ungulates to humans. The resinous roots have been an important medicine for humans for countless eons. 

This plant grows all over western North America. The USDA range map shows it growing as far east as the Dakotas, as far south as the US/Mexican border and throughout western Canada as well. 

Spring

As the snows are receding in the valley, balsam root offers its first gifts of the growing season. Locating last year’s foliage, smashed flat by the heavy snow, we can find the beginning sprouts of this year’s growth. These sprouts are best eaten when they are about an inch in length. As some of the first fresh food to appear, these sprouts are a welcome sign of the turning of the seasons. 

We harvest these sprouts by taking only one or two from each plant we walk by to ensure plenty of new growth for the plant. We’ve eaten them raw or cooked them in stir-fries and soups and we mostly prefer them raw, eating them one by one as we harvest from large stands. The sprouts have a strong resinous taste that is mildly pungent and overall pleasant. 

We’ve read ethnobotanical reports of the roots from very young plants being eaten. We’ve tried this multiple times, harvesting very small roots - about the diameter of a pencil - and cooking them for extended periods of time, but have yet to yield anything other than a hard woody root that is not edible. 

As the spring continues on, the sprouts grow into leaves and flower stalks, both of which can be peeled and eaten, again taking precautions not to over harvest from one plant. 


In late April the hillsides are turning green, the first flowers are beginning to emerge and the anticipation of yellow hillsides fills the community. Talk at the farmer’s market centers around whether this will be a good flower year or not. Tourists ask, what are those wild sunflowers on the hills?

The leaves are large and arrow shaped, hence the common name. Ethnobotanical reports indicate these large leaves were poulticed and used on burns and wounds. 

Recently, someone commented to me that this flower grows like a weed, but I was quick to interject. Although it’s very common in our valley, arrowleaf balsamroot plants take many many years to mature and are difficult to transplant. When we harvest this plant we harvest with respect for each plant, understanding the abundance of this plant is a gift of the valley. 

Summer 

The last of the flower show is fading by mid June, and July and August will bring the next gifts of this sunflower plant, seeds! 


We’ve experimented harvesting the seeds in a couple different ways over the past years. There is a small window of time to optimally harvest the seeds. We like to collect the seed heads when the seeds are visually mature but the head is still somewhat tight. Mature seeds are black instead of a dark green color. If we wait too long to harvest the seeds then many have already been eaten or have fallen to the ground. 

We harvest the whole seed head and then lay them out on a sheet in the sun. As the seed head dries, the mature seeds will fall from the seed head and onto the sheet. The seed heads can be further shaken to loosen a few stubborn seeds, but not overly so. 

One year my husband did his best to get every single seed from the seed head. He diligently split open the seed heads in his quest for thoroughness. He discovered this is not the way to go about it. Besides getting a few stubborn mature seeds, this method will also remove any seeds that are not mature and. worse, will also loosen irritating hairs that will then have to be painstakingly removed from the seeds. 

It’s far better to only take what gingerly falls from the seed heads and leave the rest to go back to the earth. We find that in a couple of hours one person can gather about a quart of seeds. I do not know the exact nutritional value of the seeds but I assume that, like most seeds, they are high in proteins and oils, making them a good source of food. 

The seeds are quite small. Shelling these is not an energy efficient way to spend your time and the shell is hard enough to be annoying to eat. We’ve tried milling the whole seeds by grinding them with a mortar and pestle but the seeds go rancid amazingly fast. Roasting them does not soften the shell quite enough to make them pleasant to eat. 

The best way we’ve found to eat them is by putting them in our stew pot and simmering them for several hours. 

Seed heads are an important food source for birds, rodents and deer so we consciously harvest these from a large area and leave plenty for the wildlife.  

By mid-August the arrowleaf balsamroot is a brown shell of its spring glory. The once green leaves are brown and crinkled and only a few dried out seeds heads stand where hundreds of yellow flowers shone just months before. But, as herbalists, we know the plant is still pulsating and alive beneath the soil surface. 

Autumn

The root is the main part used as medicine. Herbalist Michael Moore describes arrowleaf balsamroot as a cross between echinacea and osha. I can’t personally attest to arrowleaf balsamroot being an immunomodulator but it certainly has an affinity for the respiratory system. 


Like many resins the root is decidedly pungent in taste. A small taste of the root and I feel the warming and drying qualities as the energy goes to my lungs, creating the need to clear my throat or cough. Oftentimes taking a few drops of the tincture creates a reflex of taking a large breath. 

I recently was teaching a class to a group of students, many of whom had a cold. Passing around the tincture of arrowleaf balsamroot, students with congestion in their lungs reported feeling expectoration from their lungs and students with head colds felt stuck mucous in their sinuses start to release.

I prefer to use arrowleaf balsamroot as a fresh root tincture in 95% alcohol. I often combine this tincture with elderberry, osha and honey. 

Arrowleaf balsamroot is a stimulating expectorant, stimulating diaphoretic, and an antimicrobial suitable for sore throats. 

I’ve received the best results when using it as a simple for productive coughs that last beyond other symptoms of the original cold or flu. 

For sore throats I like to mix 10 - 20 drops of the tincture with a spoonful of honey that is then swallowed. I often combine it with a tincture of cottonwood buds.  

I have yet to use arrowleaf balsamroot for a UTI, but Michael Moore describes arrowleaf balsamroot as an disinfecting diuretic. Darcy Williamson reports that taken in too large of a dose it will create kidney irritation. 

For external use it infuses into oil very nicely; because of the resins I use heat to extract the root. This warming aromatic oil relieves pain brought on by blood stagnation such as sore shoulder muscles or tension associated with coldness. Used as a liniment it also lends itself well to sore muscles and can also be used to disinfect wounds or kill fungi living on the skin. 

Although lacking experience with this myself I’ve seen ethnobotanical records indicating that arrowleaf balsamroot is useful for gastrointestinal complaints and toothaches. 

I only need one small root a year to make enough tincture and oil for myself and clients. Heading out into the brown forest outside of my cabin I look for plants with a modest amount of foliage indicating the size of the root. 

Large plants can be several decades old and boast a large gnarly root. These large roots can easily be 5-8 feet deep into the earth. Harvesting arrowleaf balsamroot is no easy task, so I am content with my smaller sized roots and leave the mature plants to grow. 

Besides searching for the right size I also look for plants on flat ground. Those plants on steep hillsides are doing an important job of keeping the hillside in place. Lastly, I harvest from a well-developed stand. 

Traditional style digging tool made from ocean spray and douglas fir. 

I use a traditional digging tool for my root harvests. I find sticks are often easier to use as a harvest tool than shovels since shovels can easily slice roots and can often get caught on the plethora of rocks hiding in the soil where arrowleaf balsamroots live. Patience and time rewards me with a taproot the size of a large carrot. A hard outer bark envelopes a woody root in the center. I break apart the outer bark with a hammer, mince the inner bark and tincture them both. The resins from the root cover the cutting board, knife and hands. Alcohol works well to clean them off. 

Winter

In the north, winter is a time for animals and plants to rest. In our valley the ground is covered with many feet of snow blanketing all the plants beneath the soil. Arrowleaf balsamroot rests in its roots, waiting until spring to bring forth its many gifts once more. 

Above ground we nestle next to the wood stove and give our thanks for the medicine of arrowleaf balsamroot.
Plant Specifics
Common Name: Arrowleaf Balsamroot
Scientific Name: Balsamorhiza sagittata
Family: Asteraceae

Description: Perennial growing throughout western north America as far east as the Dakotas, as far south as California and throughout western Canada as well. It grows in a variety of habitats, including forested mountains to the sage brush steppe. 

The taproot is covered in a hard bark and is fairly resinous. Depending on the growing habits and age of the plant, the root can reach several meters into the ground and weigh over 30 pounds. 

The leaves can be fairly large, around 20 inches in length and are arrow shaped or triangular. 

The flower looks like a sunflower with yellow ray flowers. The entire flower head is about the size of a small fist. 

The seeds are the size of a grain of rice and are darkly colored ranging from green to brown to black depending on the maturity. 

Properties: Pungent, warm/dry, stimulating expectorant, stimulating diaphoretic, anti-microbial, anti-fungal

Strong affinity for the respiratory system. 








Sunday, December 4, 2011

Digging a well when you're thirsty...


Photo by Ananda Wilson
Curing a disease once someone is already ill is like digging a well when you are thirsty.
- Chinese saying

The poignant quote above illustrates our common cultural disillusionment with health. Many of us are only motivated to change our daily habits once illness has arrived. When instead our quest for vibrant health can be sought in every action we take and well before disease sets in. 

For some people preventive health may mean forcing unpleasant activities upon themselves in the name of good health (restrictive diets and harsh detoxes to name a couple). 

But what if instead our daily search for vibrant health was filled with joy, pleasure and empowerment?

I recently signed up for this new course from herbalist Ananda Wilson which accentuates pleasure and self-care as a means of more holistic journey towards health. 

I have absolutely LOVED Ananda's course so far. Her herbal products are beyond what I have ever seen in the herbal world and her content has already created many positive shifts in my life. 

You can read more about this course below or by visiting Ananda's site here

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Tired of "calgon" - toxic ways to relieve stress and desire natural care


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How does the Lady's Slipper Ring work?


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I sew together my years of work in Wilderness training, Red Tent Temple leading, Herbal Medicine, and Movement instruction, to bring you the distilled and powerful essences of self care and creative health. My immense joy in life is to help others awaken their thinking body, feeling mind and intelligent heart


You will receive personally written content to compliment each herbal collection. The content is meaningful and action based, simple yet profound, malleable and achievable even for busy women. 


The written content comes in 6 sections:


1) Invitations ~ A set of Invitaitons for the month: activities for self care, journal exercises, and a co-created or prompted daily practice for you, seasonally aligned. 


2) Potions ~ An herbal recipe or two to suit the month's theme.


3) Tasks/Checklist ~ To help you feel organized


4) Supplemental Resources ~ Suggested Books and Websites in support of the month's theme


5) Collection Descriptions ~ Explanations for each Collection with Intentions/Suggestions for uses.


6) Adornments ~ A random surprise extra - inspirations, playful ideas, and miscellaneous wisdom. 




You will receive a three-piece herbal collection every month, handcrafted by yours truly. With over 20 years experience in herbal medicine making and formula blending, and a lifetime of herbal healing experience as a second generation herbalist. I bring you decadent, fine botanical potions created with wildcrafted and organic plants, exquisite essential oils, and absolute lusciousness for your healing wholeness. 




In all, Lady's Slipper Members receive:


One complete three piece masterfully handcrafted herbal collection, Monthly, Valued at over $75.00 ea


~ Rich and Engaging Support Content Monthly (as described above, via PDF) 


~ One Q&A Support email exchange Monthly **ONLY available to 3 more members **


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You can learn more about the Lady Slipper Ring by clicking here. 


December's lovely herbal selection. 
As a side note: Every week I get several requests from people and companies wanting me to do a blog post about their product or service. If you're a frequent reader of my blog you'll know that none of these requests are ever realized on my blog. I am posting this more "advertising" post because I feel so strongly about this course. I am receiving no financial compensation for this support. 

Friday, December 2, 2011

Discovering Tao

Tracy and I have started a new blog together:  Discovering Tao: Training For Awakening Oneself.

My first posts there:

Staying Flexible features this video:



If You Want To Rebel, Act Kind about Pancho Ramos Stierle, the guy meditating surrounded by police in war-gear.

Meditation Disturbs The Peace?

Valerian on Photo Friday


Valeriana officinalis growing
on a volcano in Central France

Today's Photo Friday is one of my favorite plants, the notorious valerian. 


I rely on valerian often in my life to help with muscle pain and spasms in my back, for menstrual cramping and for relaxation and sleep. I am a valerian girl. 


While valerian is a relaxing nervine, sedative and anti-spasmodic to the majority of people, a significant amount of people react in the opposite way to valerian. Instead of settling in for a deep sleep they find themselves agitated and very awake. 


I recommend starting out with low doses of valerian to figure out which category you're in. 


I use valerian tincture in fairly large doses for myself. Two dropperfuls at night will konk me out almost immediately. 


I also use it as a fomentation for back pain and muscle spasms. I generally combine it with ginger. 


One of the best uses of valerian is for those dry spastic coughs that often accompany the end stages of a cold or flu. You know those annoying coughs that often become worse when lying down, preventing sleep. 


To address these debilitating coughs I do two things. I take marshmallow root and/or linden leaf/flower infusions during the day to address the dryness. Then valerian root tincture at night to stop any residual coughing. For myself,  I just keep dosing the tincture until I pass out. This generally means two dropperfuls initially and then a dropperful as necessary. 


Various species of valerian can be used with similar results. I'd love to hear what species of valerian you're using. 
Valeriana sitchensis growing on Mt. Hood
in Oregon. 



Valerian sitchensis grows wild in the mountains above my home, but since I also grow Valeriana officinalis in my garden, I rely on that for most of my medicine. 






I planted this Valeriana officinalis a couple years ago. I purchased the sprout from Crimson-Sage Nursery and then planted it without really knowing what to expect. 


At the time it was about 12 inches tall. 


By the second year this valerian was easily 8 feet tall in my garden. 


The valerian is the tall green stuff at the
back of the planting box. 


Besides offering fragrant and beautiful blooms it also supported some great wildlife viewing opportunities. Here's a goldenrod spider having a little snack. 


The goldenrod spider can change it's color from yellow to white depending on it's
current flower home. (As you might imagine it is yellow when found on goldenrod flowers.)




I've tinctured the flowers of valerian but haven't had a chance to use them yet as medicine - have any of you? Please share in the comments below. 


Valeriana officinalis leaves



This fall I dug the roots of the valerian I had planted two years ago. It was easy to split the plant in two and then replant the second half. 






If you don't do this occasionally with the valerian in your garden the roots will become more woody and have less essential oils. 







Depending on who you ask, valerian roots can smell deeply earthy or like gym socks.   


When harvesting and preparing the roots for medicine  we want to process them minimally to avoid damaging the volatile oils in the plant. 






To make a tincture I put the roots in a bowl of coldish water and gently swished the roots around. This was to get most of the dirt from the roots. I didn't scrub the roots. 







The result was mostly clean roots. I chopped these finely and then tinctured at 1:2 at 75%. 




When this is done macerating I'll filter this really well to capture any stray pieces of dirt that made it to the batch. 


Valerian is easy to grow, can also be wildcrafted and provides effective relief for pain and sleeplessness for most people. I've relied on valerian so many times for aches and pains and periods of insomnia that I have a strong love affair with this potent smelling creature. 






Further resources: 
Mini-monograph on valerian (with a story about cats)
Another small monograph on valerian


Very thorough monograph on Valerian (by ABC) pdf





Sunday, November 27, 2011

Chamomile - An excerpt


The following is an excerpt from my latest ebook: 
Herbal Remedies for Children 
During the Cold & Flu Season. 

This ebook is on sale for $10 

Purchase this ebook before midnight on Monday, November 28th you'll receive several bonuses including an ebook on Herbal Gifts for the Holiday season and two fun herbal crafts. 


To buy the ebook, click on the Add To Cart button below:

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Now about Chamomile (Matricaria recutita)...

One of my first memories of using plants for medicine was delivered through Beatrix Potter and her adventures with Peter Rabbit. You might remember the day that Peter Rabbit narrowly escaped a harrowing ordeal in Mr. McGregor’s garden. Once he was safely home his mother gave him a cup of chamomile tea before putting him to bed. How quaint! Perhaps it was because of this pre-school impression that I didn’t take this herb very seriously. 


Now, many cups of chamomile tea later, I understand what makes chamomile so extraordinary. It provides significant results while being safe and gentle for practically everyone. 



As Peter Rabbit’s mother knew, chamomile is soothing and calming; perfect after those stressful days in the garden or at work. It not only helps to promote rest, but it also helps to mediate pain and inflammation. In fact, chamomile is so effective at reducing inflammation that it has been studied extensively for this ability. 


If you type its scientific name (Matricaria recutita) into PubMed (a government listing of biomedical studies), you’ll see it has been proven effective both for addressing phlebitis caused by chemotherapy treatments and for stopping allergies by inhibiting the histamine response. 

From an herbalist’s perspective, chamomile is considered bitter, slightly warming, and relaxing. What does this mean and why does it matter? 

Herbalists don’t simply study what herb is good for what condition. Instead, each plant is analyzed on a variety of therapeutic levels. One important aspect of this is the plant’s ability to warm or cool a person. Have you ever eaten really spicy wasabi and then felt your sinuses drain? Or eaten a fresh slice of watermelon on a hot day and felt cooled and refreshed? If so, then you’ll know exactly what I am talking about. 

Every medicinal plant has these characteristics to some degree or another, and understanding these actions helps herbalists to be more effective at choosing which plant can help a particular person. Chamomile, as just described, is relatively neutral but perhaps slightly warming. Generally, our more neutral plants can be taken by most people and in higher amounts without causing unwanted effects. 

The taste of a plant is also very important in understanding the plant’s actions. The bitter taste on our tongue creates a cascade of events that promotes our digestive function. From stimulating saliva (our first digestive juice) to various enzymes in the stomach, liver and pancreas, one can argue that the bitter taste is needed at every meal. A strongly brewed cup of chamomile provides this bitter taste, thus promoting healthy digestion. 


Chamomile can be especially beneficial for people with a “nervous stomach” as it both calms and soothes while stimulating digestive function. It can also be used by people with digestive inflammation (such as heartburn or IBS) to mediate inflammatory levels in the gut mucosa. 

Furthering helping with digestion are chamomile aromatic qualities which break up stagnant digestion (think bloating and the bowling ball that won't leave your stomach). 
Chamomile has many applications for common complaints. Besides helping to relax the nervous system chamomile also can relax muscle tissue. Women may find their menstrual cramps abated with a strong cup of chamomile tea, or diminished by rubbing their abdomen with oil infused with chamomile blossoms. 


Any mother whose colicky or teething child has been soothed to sleep (or simply quieted) by chamomile will tell you this is beneficial stuff! 


If you’ve ever stuck a chamomile tea bag into a cup of hot water for five minutes, then you’ve experienced chamomile as a delightful and slightly sweet tea. To get more therapeutic results, use more chamomile and steep for longer. I generally use 1/2 cup of flowers to a pint of just-boiled water and I let it steep for 20-30 minutes. The resulting brew is decidedly less sweet than a cup of tea but this stronger concoction provides more relief for many of the issues listed in this article. 

Besides drinking this strong infusion, it can also be used on skin as a rinse or added to bath water to relieve itching of mild rashes. Chamomile is also used as a tincture, a glycerite and as an infused oil. 

Saturday, November 26, 2011

Study Indicates Prostate Cancer Is Reversible By Diet




According to the National Cancer Institute, each year in the U.S., 240,890 men get diagnosed with prostate cancer, and 33,720 men die from it.

According to the American Cancer Society,

"About 1 man in 6 will be diagnosed with prostate cancer during his lifetime. More than 2 million men in the United States who have been diagnosed with prostate cancer at some point are still alive today.

"Prostate cancer is the second leading cause of cancer death in American men, behind only lung cancer. About 1 man in 36 will die of prostate cancer."


I have a family history of prostate cancer, so I have a personal interest in prevention and remedy for this disease of civilization.

According to some people, whole grains and legumes cause or promote the diseases of civilization, including cancer.

If this disease is caused by eating grains and legumes, then any diet based on grains and legumes should promote cancer.  If you give men living with prostate cancer a diet rich in whole grains and legumes, you should see a promotion of the cancer.

My friend, Gordon Saxe, M.P.H., Ph.D., M.D., professor of medicine at U.C.S.D.,  has actually tested this hypothesis, albeit unintentionally.

Gordon has lead pilot research in which men with diagnosed with prostate cancer were taught to eat a diet consisting of whole grains, legumes, vegetables, fruits, nuts, and seeds, while eliminating animal  products, based on evidence [discussed here] that this dietary pattern may reduce the risk or progression of prostate cancer.

If whole grains and legumes promote prostate cancer then these men should have had an accelerated progression of their cancers.  However, in the first study, over six months, this intervention produced just the opposite effect:  a 100-fold reduction in the rate of rise of their disease, as measured by the rate of change in levels of prostate-specific antigen (PSA).  As stated by Saxe et al:

"The rate of PSA increase decreased in 8 of 10 men, while 3 had a decrease in absolute PSA. Results of the signed rank test indicated a significant decrease in the rate of increase in the intervention period (p = 0.01). Estimated median doubling time increased from 6.5 months (95% confidence interval 3.7 to 10.1) before to 17.7 months (95% confidence interval 7.8 to infinity) after the intervention. Nine of 10 participants in the study had reduction in the rate of rise of their PSA, a marker for progression of disease."
When 9 of 10 people respond in the very same way to an intervention, in this case with a reduction in rate of rise of PSA, this tends to suggest that the effect is no accident and most likely indicates a definite therapeutic effect of the intervention.

In the second study, involving 14 men, Saxe et al produced a similar result.  In this second study they explored the biological mechanisms involved:

"During the first 3 months of the intervention, as both median WHR and body weight declined significantly, the median rate of PSA rise not only declined but became negative, reflecting a slight reduction in absolute PSA and possibly disease regression in patients with absolute reductions. Conversely, during the second 3 months of the intervention, when median body weight increased (though not significantly), median PSA began to rise again, albeit more slowly than during the period prior to Baseline."
This second study suggested that weight-related metabolic changes may have mediated the reduction in rate of PSA increase.  In other words, the intervention resulted in a loss of body fat and concommitant metabolic changes related to reduction of body fatness, including an increase in sex hormone binding globulin, that influence prostate cancer.

"Assuming that the attenuation of PC progression was mediated by weight-related metabolic changes, a question arises as to what aspect of intervention brought about the observed reduction in adiposity. Earlier 53, we described large increases during months 0–3 in intake of whole grains and vegetables, food groups which are fiber and water-rich, very low in fat, and therefore of low energy density. However, intake of these foods declined slightly during months 3–6. Weight loss during the first three months may possibly have resulted from replacing energy-rich foods with energy-poor foods, and the slight increase in body weight during the second three months may have resulted from a small degree of dietary recidivism." 
So this intervention, based on increasing intake of whole grains, legumes, etc., resulted in body fat reduction during the period when the subjects ate the most of these foods, and body weight increased during the period when these subjects ate less of these foods.  This clearly undermines the idea that diets rich in grains and legumes cause two of the major diseases of civilization, i.e. obesity and cancer.

Saxe et al consider the possibility that any diet that induces weight loss may reduce cancer progression.
"A second question that naturally arises regarding the reduction in adiposity is whether it matters, in terms of effects on prostate cancer progression, how it is achieved. One aspect of this question has to do with the preferred dietary strategy for reducing energy intake. Another facet regards whether it is more desirable to increase energy expenditure or decrease intake to achieve this end. Although our study and its findings did not address these issues, they remain important ones that warrant consideration in the planning and design of future behavioral approaches to the management of progressive PC. What can be said is that while both a plant-based diet and a high-protein, low-carbohydrate diet high in foods of animal origin (such as the popular Atkins diet) may both result in weight loss, the former is far more consistent with the dietary cancer prevention guidelines of various agencies (69).54 "
Some people reject those cancer prevention guidelines of various agencies, which emphasize increased consumption of whole plant foods and decreased consumption of animal products, claiming that whole grains and legumes are the true causes of diseases of civilization.   These two studies, among others, weaken that claim. 

So far, the only studies I can find testing the effect of a low-carbohydrate diet on prostate cancer were done with mice, not men.  In this one, researchers from Duke Prostate Center fed mice with prostate cancer either a "Western" diet,  "low-fat high-carbohydrate" diet, or a zero-carbohydrate diet.  The results:

"Fifty-one days after injection [with xenograft tumors], NCKD mice tumor volumes were 33% smaller than Western mice (rank-sum, P = 0.009). There were no differences in tumor volume between low-fat and NCKD mice. Dietary treatment was significantly associated with survival (log-rank, P = 0.006), with the longest survival among the NCKD mice, followed by the low-fat mice."
I don't have access to the full text, but if done in a typical fashion, all diets would have been pellets made from isolated nutrients (e.g. casein, starch, sugar, etc.) so this can't tell us much about what would happen in humans if we compared a whole foods vegan diet (whole grains, legumes, vegetables, fruits, nuts, seeds) to a zero-carbohydrate diet (meat and fat only).  The effects of a casein-based zero-carbohydrate diet on mice might be very different from the effects of a meat-based zero-carbohydrate diet on humans.

In a second study, Masko et al fed mice diets containing 0, 10, or 20 percent carbohydrate and again injected them with prostate cancer cells.  As a 'control' they fed a group of mice a 12% fat diet, but they did not inject cancer cells into these mice--which to me means they weren't much of a control group, because they differed from the others not only in dietary composition but also in absence of tumor injection.

The full text of this study tells us the components of all diets:  corn oil, lard, milk fat, casein, dl-methionine, dextrine, maltodextrine, corn starch, sucrose, and isolated vitamins and minerals. 

In the low-fat arm, 72% of calories came from carbohydrate, and 50% of total calories came from sucrose, which means that about 25% of total calories came from refined fructose.  Meanwhile, in the 10% and 20% carbohydrate arms, all of the carbohydrate was provided in the form of corn starch. 

This makes me wonder again about diet composition in the other Duke University study cited above.  Were those mice on the low fat diet also eating a 50% sucrose/25% fructose diet?  If so, did this rig the study, intentionally or not, so that the low fat group would have more body fat and shorter lifespan than the zero-carbohydrate group? 

Moving on, all the mice got all of their protein from casein-plus-methionine, none ate any meat.  Most people eating low carbohydrate diets eat cooked meats, not isolated casein, as their main protein source.  Meat is nutritionally complex, and affected by cooking process, in ways that may result in it having a different effect on prostate cancer than casein-plus-methionine.  For example, unlike the casein-methionine mix fed to these mice, meat contains heme iron and if cooked at high heat, heterocyclic amines, all of which have been linked to prostate cancer causation or promotion [e.g. Sinha et al full text].  So it is not clear how a study of mice eating a low carbohydrate diet wherein casein is the main protein will apply to people eating low carbohydrate diets wherein cooked meat, poultry, and fish are the main protein sources.

Masko et al found that the survival rates of the mice in the 0, 10, and 20 percent carbohydrate groups were similar.  They liked this finding because, as they say, people find it extremely difficult to follow zero-carbohdyrate diets, so now they are ready to test the 20 percent carbohydrate diet on human prostate cancer patients. 

Masko et al also found that the mice in the 20% carbohydrate group had the lowest insulin level, about which they comment:

"It was unexpected that the lowest levels of insulin were observed in mice fed with 20% carbohydrate, but there are possible explanations for this phenomenon. First, there is always the possibility for a type I error in the analysis. Second, it is known that low-carbohydrate diets promote insulin sensitivity in animals (38) and humans (39, 40). Thus, it is possible that a diet containing a small amount of carbohydrates may actually improve insulin sensitivity compared with a diet completely lacking of carbohydrates."
Perhaps unknown to Masko et al, it is also 'possible' that a diet containing an even large amount of carbohydrate may actually improve insulin sensitivity compared to a diet with only 20% carbohydrate. In 1971, Brunzell et al [abstract only] evaluated the effect of increased dietary carbohydrate at the expense of fat in humans, both non-diabetic and mildly diabetic.  In the New England Journal of Medicine they reported that after feeding these subjects a diet providing 85 percent of energy as carbohydrate for 10 days,

"Fasting plasma glucose levels fell in all subjects and oral glucose tolerance (0 to 120-minute area) significantly improved ..... Fasting insulin levels also were lower on the high carbohydrate diet; however, insulin responses to oral glucose did not significantly change. These data suggest that the high carbohydrate diet increased the sensitivity of peripheral tissues to insulin."
 An diet supplying 85 percent of energy as carbohydrate is by necessity very low in fat, so perhaps Brunzell et al could have emphasized that this very low fat diet increased insulin sensitivity.  The mice of Masko et al that got the 20 percent carbohydrate diet had a lower fat intake than the mice on the zero-carbohydrate diet; rather than increasing carbohydrate being responsible for promoting insulin sensitivity, perhaps it is reducing fat (replacing it with starch) that does the trick. 

Anyway, the Masko et al study has a few features that make me skeptical that they will have similar results in humans.  I feel curious to see if their approach will have results as good as those found by Saxe et al.